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Osteomyelitis (Refractory)

Refractory Osteomyelitis refers to a bone or bone marrow infection that is not responding to conventional treatment (antibiotics.) Certain bones in the body, including the jaw bone, the spine and the long bones of the limbs are susceptible to infection due to the limited blood supply. With the rise of antibiotic resistant microbes, it is imperative that alternatives to antibiotics be considered. Depending on the location of the infection and the severity, significant pain and disability can result. Infections can arise from injuries, surgeries, infections in other parts of the body or teeth with root canals.

The Rationale for Hyperbaric Oxygen Therapy

A Horse with Osteomeylitis

Refractory Osteomyelitis is an Undersea and Hyperbaric Medical Society (UHMS) approved condition. HBOT has been scientifically proven to:
  • stimulate fibroblasts to increase collagen deposition
  • promote new blood vessel growth (angiogenesis)
  • stimulate osteoclasts (bone resorbtion)
  • stimulate osteoblasts (bone building)  
  • potentiate antibiotic activity 
  • may disrupt biofilms
  • a potent anti-inflammatory effect
  • immunomodulatory effect, strengthens immune system
  • delivers oxygen to hypoxic tissues
  • reduces pain
  • Increases stem cell circulation

Biofilms in Osteomyelitis

It has been reported by Wolcott et al. that osteomyelitis has a biofilm component. Biofilm is a form that multi-kingdom bacteria can take in the body, that are strongly antibiotic and immune resistant. It is believed that the chronicity of many infections can be attributed to this bacterial form. HBOT has been shown to be a effective potentiator of antibiotics in many biofilm infections, it remains to be seen if HBOT has a direct anti-biofilm effect. For more information visit our biofilm page. 

Scientific Resources
  • 2018 - Effectiveness of Hyperbaric Oxygen Therapy for the Management of Chronic Osteomyelitis: A Systematic Review of the Literature
  • 2009 - Adjunctive Therapies in the Treatment of Osteomyelitis - Free Article
  • more soon...
UHMS Osteomyelitis Page
14 Approved Indications

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#10-1009 Allsbrook Rd
Parksville, BC, Canada
V9P2A9

1-877-954-0335
250-954-0335 

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UHMS Approved Conditions

Air or Gas Embolism
CO, Cyanide Poisoning
Gas Gangrene

Crush Injury, Compartment Syndrome etc.
Decompression Sickness
Problem Wounds, CRAO
Severe Anemia
Intracranial Abscess
Necrotizing Soft Tissue Infections
Refractory Osteomyelitis
Delayed Radiation Injury
Compromized Grafts and Flaps
Acute Thermal Burn
ISS Hearing Loss  (ISSHL)

Investigational Conditions

Lyme Disease
Chronic Fatigue Syndrome

Shingles / Herpes Zoster
Headache
Calciphylaxis

Stevens-Johnson Syndrome
Livedoid Vasculopathy
Venous Stasis Ulcer
Pressure Ulcer
Scleroderma, Raynauds
Multiple Sclerosis
Type 1 Diabetes
Psoriasis
Arthritis
Pyoderma Gangenosum
Stroke
TBI and PTSD in Vets
Epilepsy

Post Concussion Syndrome
Alzheimer's Disease
Autism

Crohn's, Colitis
Peripheral Artery Disease
Erythromelalgia
CRPS, RSD
Peripheral Neuropathy

Degenerative Disc Disease

Fibromyalgia
Cancer
 (General)
Fractures

Glaucoma
Macular Degeneration
Macular Edema
Periodontal Disease
Dental Implants
BRONJ
Type 2 Diabetes


...more conditions soon