Fractures range from straightforward breaks to open injuries with major damage to skin, muscle and blood vessels. Stabilizing the bone, treating wounds and infection, and following a rehabilitation plan are the foundations of care. Evidence about severe traumatic injuries should not be applied automatically to an uncomplicated fracture.
The 2022 HOLLT randomized trial studied people with open tibial fractures receiving standard trauma care with or without HBOT. Its primary combined outcome of early infection or tissue necrosis was not significantly different between groups. Some secondary outcomes, including tissue necrosis and later complications, favoured HBOT. This suggests a possible role in selected severe injuries, rather than proof that HBOT routinely speeds healing of every broken bone.
Jawbone damage and poor healing associated with certain bone-strengthening medications.
Broken bones ranging from simple cracks to complex injuries involving surrounding tissue and circulation.
A persistent or recurring bone infection that has not resolved despite appropriate standard treatment.